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ARCOXIA is indicated in adults and adolescents 16 years of age and older for the symptomatic relief of osteoarthritis OA, rheumatoid arthritis RA, ankylosing spondylitis, and the pain and signs of inflammation associated with acute gouty arthritis. ARCOXIA is indicated in adults and adolescents 16 years of age and older for the short-term treatment of moderate pain associated with dental surgery. The decision to prescribe a selective COX-2 inhibitor should be based on an assessment of the individual patient's overall risks see sections 4. As the cardiovascular risks of etoricoxib may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. The recommended dose is 30 mg once daily.
Nonsteroidal antiinflammatory drugs NSAIDs, including selective cyclooxygenase COX -2 inhibitors, have come to play an important role in the pharmacologic management of arthritis and pain. Clinical trials have established the efficacy of etoricoxib in osteoarthritis, rheumatoid arthritis, acute gouty arthritis, ankylosing spondylitis, low back pain, acute postoperative pain, and primary dysmenorrhea. Etoricoxib was generally well tolerated in these studies with no new safety findings during long-term administration.
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