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The aim of our study was to compare the efficacy and safety of oral mesalazine with mesalazine suppositories in patients with active ulcerative proctitis. Patients were evaluated at study entry and after two and four weeks. Efficacy evaluations included a disease activity index, which represents a score with four variables: stools frequency, rectal bleeding, mucosal appearance, and physician's assessment of disease severity. Histologic activity was also assessed at study entry and after two and four weeks in accordance with the criteria by Truelove and Richard. Safety assessment included clinical laboratory parameters and adverse event reports. There were no significant differences with regard to baseline comparisons of demographics and severity between the two treatment groups.
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Martin (taken for 3 to 4 years) 22.10.2019
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People who need a mesalamine prescription can use Push Health to connect with a nearby medical provider who can prescribe generic mesalamine, including Lialda tablets, when appropriate and safe to do so. Mesalamine Lialda belongs to a class of medications known as anti-inflammatory agents. Also known as 5-aminosalicylic acid or 5-ASA, mesalamine's mechanism of action is not completely clear.
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