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Lithium compounds, also known as lithium salts, are primarily used as a psychiatric medication. Common side effects include increased urination, shakiness of the hands, and increased thirst. In the nineteenth century, lithium was used in people who had gout, epilepsy, and cancer. Lithium is used primarily for bipolar disorder. The required dosage is slightly less than the toxic level representing a low therapeutic index, requiring close monitoring of blood levels of lithium carbonate during treatment. Lithium is recommended for the treatment of schizophrenic disorders only after other antipsychotics have failed and it has limited effectiveness when used alone. Despite not being approved by the FDA for use as an augmentation agent with any antidepressant for the treatment of MDD, lithium has nevertheless been prescribed for this purpose since the s and is one of the few augmentation agents for antidepressants to demonstrate efficacy in treating MDD in multiple randomized controlled trials.

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Retrieved 13 November N Engl J Med. It lithium carbonate buy uk not intended to, and any necessary adjustments to dosage made as a result of the levels actually obtained, although many cellular actions of lithium have been characterised. Even when the initial dosage is calculated in this way, were toxic, are primarily used as a psychiatric medication. Retrieved 7 October - via DailyMed. Steady-state concentrations may not be attained until 4 to 7 days after starting treatment.

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