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Even after you've decided to take estrogen replacement therapy ERT, the decision-making isn't over. The best type of hormone replacement therapy HRT depends on your health, your symptoms, personal preference, and what you need to get out of treatment. For example, if you still have your uterus, then estrogen will be given in combination with the hormone progestin. Estrogen is also sometimes not well absorbed, especially if you take certain medicines or have stomach problems. It may also increase your cholesterol, because it is metabolized in the liver. Because the estrogen is absorbed right through the skin, don't let other people in your family touch these creams or gels.

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