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Verapamil is a calcium channel blocker, it treats high blood pressure relaxing and widening blood vessels. Pharmacological influence of Calan is explained by braking of a flow of calcium ions through the slowed-down calcic tubules of cellular covers of smooth muscle structure of vessels and a cardiac muscle. Calan is prescribed if it was diagnosed paroxysmal supraventricular tachycardia except WPW syndrome, sinus tachycardia, premature atrial contraction, blinking and atrial flutter, stenocardia inc. Isoptin is a calcium ion antagonist of the phenylalkylamine group. It improves myocardial perfusion, eliminates coronary spasm, reduces myocardial oxygen demand.

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  • Isoptin SR verapamil HCl is a calcium channel blocker used to treat hypertension high blood pressure, angina chest pain, and certain heart rhythm disorders.
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Diltiazem is contraindicated in patients with sick sinus syndrome SSS. Use of diltiazem in patients with SSS may lead to severe hypotension, bradycardia, or asystole.


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