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PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes. Diclofenac was the product of rational drug design based on the structures of phenylbutazone, mefenamic acid, and indomethacin. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. It is often used in combination with misoprostol as a gastro-protective agent in patients with high risk of developing NSAID-induced ulcers. Diclofenac reduces inflammation and by extension reduces nociceptive pain and combats fever. Label, 17 It also increases the risk of developing a gastrointestinal ulcer by inhibiting the production of protective mucus in the stomach.

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It is used to reduce pain, swelling, and inflammation. The diclofenac potassium tablets are used for short-term relief of pain and inflammation, such as pain caused by sprains, surgery, dental work or menstrual cramps.

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